The central question of our research group is to explore the pathophysiology of behavioural and movement dysfunctions associated with rare diseases with developmental disorders (mirror movements) and behavioural and motor dysfunctions (dystonia/ Tourette syndrome).

We develop a common approach combining:

a) in vivo and biological study of animal models combined with non invasive explorations of the related genetic forms of human diseases and

b) multimodal neuroimaging-neurophysiology analysis of motor and non-motor cerebral networks in various phenotypes of these rare disorders with the objective to develop innovative therapeutics...