Full time researcher (Paris Brain Institute), CNRS (Delegation Paris-B Ile de France), Paris, France.

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The main thrust of my research is to study the functional networks involved in fine motor skills with a translational pathophysiological approach.

In particular, my work aims to test new hypotheses concerning the physiological interdependence of cerebellar, striatal and cortical circuits during learning. I focus on pathological models with specific striato-cortical and/or cerebellar-cortical dysfunctions (dystonia, essential tremor, Parkinson's disease), and for which the possibilities of non-invasive treatments are limited.

In the implementation of my projects, I use non-invasive neuromodulation of cerebellar inputs and neuroimaging/electrophysiology to record the effects of neuromodulation on the spatial and temporal characteristics of the interactions between the nodes of these circuits. These combined neuromodulation, multimodal imaging approaches are essential to extract information about the specificity of sub-circuit interactions and to develop new experimental therapeutics.

In the long term, the aim is to deepen our understanding of brain function at the level of the genesis of rhythms (the support of communication between the nodes) which condition fine motor skills, learning and brain plasticity.