Mouton Laura
PhD
Laura Mouton holds a PhD in medical imaging physics from the Paris-Saclay University.
She is currently a postdoctoral fellow at the Center for Neuroimaging Research at ICM. She has been working in preclinical MRI with the 11.7T MRI Bruker scanner to study the mouse brain either in pathological or in healthy conditions for over 5 years.
2016 - 2020 : PhD in Physics with a specialization in medical imaging (Paris-Saclay University).
Supervisor: Denis Le Bihan(NeuroSpin, CEA, Saclay, France). Project: development of diffusion-weighted MRI for the characterization of radio-induced neuropathological injuries in a mouse model exposed to ionising radiations.
2014 - 2016 : Master’s degree in biomedical imaging(Paris Sud University)
2011 - 2014 : Graduation in fundamental physics(Lille 1 University, France)
2017 : Certificate for animal experimentation:conceptor level (Paris-Descartes University, France)
2020 : Certificate for the basic regulatory training in surgery (Vetsalius, ICM, France
Mouton L., Etienne O.,Feat-Vetel J. and et al. Noninvasiveassessment of neurodevelopmental disorders after in utero irradiation in mice :An in vivo anatomical and diffusion MRI study. Radiat Res. 2021 Apr 7. doi:10.1667/RADE-20-00136.1.
Mouton L., Ribeiro M.,Mouthon M.A. and et al. Experimental and preclinical tools to explore the main neurological impacts of brain irradiation : current insights and perspectives. In : Giorgio Seano, ed. Brain Tumors. Neuromethods - Springer - Nature 158.
Bery A.,Etienne O., Mouton L. and et al.XLF/Cernunnos loss impairs mouse brain development by altering symmetric proliferative divisions of neural progenitors. SSRN Electronic Journal. 2020 Dec 14. doi: 10.2139/ssrn.3748742.
Laura Mouton is currently involved in two main projects. The « IvMRS » project, stands for In vivo Magnetic Resonance Spectroscopy, and aims at testing the biocompatibility of implantable micro coils to better detect brain metabolites in multiple mouse models. The second project aims at detecting neurofibrillary tangles in the brain of a mouse model of Alzheimer’s disease by using dedicated and targeted contrast agents by MRI.
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